Originally i chose show the creation and destruction of a human, Instead i have chosen to show the complete cell cycle before mitosis.

 My aim has been to focus on what happens within the G1, S, and G2 phases (Interphase) . I want to make the cell an environment of its own and show the different components and their behavior, kind of like a tour of the human cell in action.

Interphase

Let’s enter the cell cycle just as a cell forms, by division of its mother cell. What must this newborn cell do next if it wants to go on and divide itself? Preparation for division happens in three steps:

• G$_1$start subscript, 1, end subscript phase. During G$_1$start subscript, 1, end subscript phase, also called the first gap phase, the cell grows physically larger, copies organelles, and makes the molecular building blocks it will need in later steps.
  

  [Do cells always grow before they divide?]
• S phase. In S phase, the cell synthesizes a complete copy of the DNA in its nucleus. It also duplicates a microtubule-organizing structure called the centrosome. The centrosomes help separate DNA during M phase.

• G$_2$start subscript, 2, end subscript phase. During the second gap phase, or G$_2$start subscript, 2, end subscript phase, the cell grows more, makes proteins and organelles, and begins to reorganize its contents in preparation for mitosis. G$_2$start subscript, 2, end subscript phase ends when mitosis begins.

The G$_1$start subscript, 1, end subscript, S, and G$_2$start subscript, 2, end subscript phases together are known as interphase. The prefix inter- means between, reflecting that interphase takes place between one mitotic (M) phase and the next.

Human Cell Structure

Be cause the human cell is so complex I'm only going to focus on the the different cell parts that are involved the Interphase. My aim is to simplify some the shapes of the cells features and use them to create my structure.

CELL COMPONENT	DESCRIPTION/ STRUCTURE	FUNCTION(S)
CELL MEMBRANE	Bilayer of phospholipids with proteins dispersed throughout	cell boundary; selectively permeable (i.e. controls what enters and leaves the cell; membrane transport)
CYTOPLASM	jelly-like fluid (70% water)	suspends organelles in cell
RIBOSOMES	RNA & protein; dispersed throughout cytoplasm or studded on ER	protein synthesis
ROUGH ER	Membranous network studded with ribosomes	protein synthesis
SMOOTH ER	Membranous network lacking ribosomes	lipid & cholesterol synthesis
GOLGI	“Stack of Pancakes”; cisternae	modification, transport, and packaging of proteins
VESICLE	Cylindrical membrane sacs	Storage and transport
MITOCHONDRIA	Kidney shaped organelles whose inner membrane is folded into “cristae”.	Site of Cellular Respiration; “Powerhouse”
LYSOSOMES	Membranous sac of digestive enzymes	destruction of worn cell parts (autolysis) and foreign particles
PEROXISOMES	Membranous sacs filled with oxidase enzymes (catalase)	detoxification of harmful substances (i.e. ethanol, drugs, etc.)
CENTROSOMES	paired cylinders of microtubules at right angles near nucleus	aid in chromosome movement during mitosis
CILIA	short, eyelash extensions; human trachea & fallopian tube	to allow for passage of substances through passageways
FLAGELLA	long, tail-like extension; human sperm	locomotion
MICROVILLI	microscopic ruffling of cell membrane	increase surface area
CYTOSKELETON	Protein strands that makeup cellular frame	Provide shape of cell, locomotion
OTHER STRUCTURES	Accumulations of substances	storage
NUCLEUS	Central control center of cell; bound by lipid bilayer membrane; contains chromatin (loosely coiled DNA and proteins)	controls all cellular activity by directing protein synthesis (i.e. instructing the cell what proteins/enzymes to make).
NUCLEOLUS	dense spherical body(ies) within nucleus; RNA & protein	Ribosome synthesis
CHROMATIN	DNA wrapped in protein forming nucleosomes	Protection of genetic material

Visually I'm taking influence from abstract visualizations and fractal geometrical patterns and movements, a clean matted sci-fi aesthetic with factory like mechanical structures, and also abstract music videos.

        

       

        

        

In these first thumbnails i was attempting visualize the cell structure as whole and experimenting with different art styles.

My Intention is for my final production to appeal to anyone old enough to understand conventions to do with birth, life, death, and rebirth/reconstruction when talking about time, space, the human mind and body. I would like to provoke the thoughts those always looking for an answer or reason behind what they may be seeing on screen, the free thinkers and self interpreters and anyone else who just likes to look a cool stuff without caring too much about what is going on. This makes my age range quite wide going from teens to adults.

In world that is seems to be gradually moving towards a technologically based future, information is traveling at extreme speeds across the planet available to anybody that owns a smartphone, tablet, pc or mac, laptops, televisions, or anybody with an internet connection, and those may not be needed in some instances. With the evolution of some capitalistic ideologies in the world , an obvious culture of indulgence and mass consumption can be seen, this mass consumption also most definitely applies to media. Any body who has owned a computer since the 80's/90's has been constantly upgrading and passing technology down to the next generation. All through out this time media through music, video, and still picture, has had a major impact on forming some of societies ideals as a collective and as subcultures. Music videos have been a way to convey many concepts and ideas the artist/s would like to deliver to their society or even humanity as a whole. This to me seems like a good way to explain my own message to a society that is always waiting for the "new thing", on any platform that is easily reached and highly interactive.  



 

I have decided to change my scenario to The Life Cycle of a cell. My vision is to show the development of a cell like a mechanically constructed world or planet being put together with divine instruments and components.

I'm aiming for my animation to show:

1.We see a ball of light being built upon to form a Construct being built from different interlocking structures (G1)

2. The construct continues to grow as we zoom and pan the different instruments in the cell the goal of mitosis is presented and suggested.

3. We observe a miss selecting of components that begins change the structure in a seeming good but ultimately negative way. This happens in (S) stage of the cells life cycle.

4. As the construct continues its growth signals of self destruction are sent the surrounding and received by construct.

5. The construct being confused tried desperately to piece its self together but it is continuously crumbling and falling apart.(G2)

6. The construct accepts its fate and finally crumbles to dust.

7. Screen goes black and then another ball light appears on screen.

I may decide to show the whole cycle of a healthy sell that achieves the goal of Mitosis.

I have taken some inspiration from Fractal geometry patterns and different movies.

        

The Bio-scientific Scenario that i have chosen is how cancer cells are formed and what causes the regular healthy cell to behave so abnormally.

To fully understand this process I've been watching a few short but highly informative videos on Youtube. There are loads of videos that can describe the full details of how cancer cells are formed and duplicated to attack and feed of the habitat the organism provides.

I'm more focused however on the the changing of the cell due to prolonged changing of selected information from within DNA. This may be brought on by an unhealthy lifestyle or habit.

My initial idea consists if a 3 act story:

The first being the growing of a brand new cell and first leads into the reason it may be corrupted

The corruption of the cell after its old age, it forgetting its purpose and believing its a young cell again, possibly causing it duplicate (maybe)

Finally, Either its imminent destruction of its self or by other cells (possibly T cells); or its ultimate success that is mass multiplication of it fatal existence.

Both endings could lead to engaging story either technically or metaphorically. I'm leaning more towards a metaphorical method of approaching this scenario.  

Roll Shot 01 from Mike on Vimeo.
Roll Shot 02 from Mike on Vimeo.